System	Major Organs or Tissues	Primary functions
Circulatory	Heart, blood vessels, blood	Transport of blood throughout the body's tissues
Digestive	Mouth, salivary glands, pharynx, esophagus, stomach, large and small intestines, pancreas, liver, gallbladder	Digestion and absorption of nutrients and water; elimination of wastes
Endocrine	All glands or organs secreting hormones: Pancreas, testes, ovaries, hypothalamus, kidneys, pituitary,thyroid, parathyroid, adrenal, intestinal, thymus, heart, and pineal, and endocrine cells in other locations	Regulation and coordination of many activities in the body, including growth, metabolism, reproduction, blood pressure, electrolyte balance, and others
Immune	White blood cells, spleen, thymus	Defense against pathogens
Lymphatic	Lymph vessels, lymph nodes	Collects extracellular fluid for return to circulation; participate in immune defenses
Integumentary	Skin	Protection against injury and dehydration; defense against pathogens; regulation of body temperature
Musculoskeletal	Cartilage, bone, ligaments, tendons, joints, skeletal muscle	Support, protection, and movement of the body; production of blood cells
Nervous	Brain, spinal cord, peripheral nerves and ganglia, sense organs	Regulation and coordination of many activities in the body; detection of changes in the internal and external environments; states of consciousness; learning; cognition
Respiratory	Nose, pharynx, larynx, trachea, bronchi, lungs	Exchange of carbon dioxide and oxygen; regulation of hydrogen ion concentration
Urinary	Kidneys, ureters, bladder, urethra	Regulation of plasma composition through controlled excretion of salts, water, and organic wastes
Reproductive	Male: Testes, penis, and associated ducts and glands. Female: Ovaries, fallopian tubes, uterus, vagina, mammary glands.	Production of sperm; transfer of sperm to female, Production of eggs; provision of a nutritive environment for the developing embryo and fetus; nutrition of the infant.