Systemic lupus erythematosus is a disease that causes inflammation of various parts of the body, especially the skin, joints, blood vessels and kidneys. It results from a malfunctioning immune system, which attacks the body instead of protecting it. As occurs in other autoimmune diseases, the immune system attacks the body's cells and tissue, resulting in inflammation and tissue damage. SLE is characterized by the production of unusual antibodies in the blood. Contributing factors may include genetics, infections, ultraviolet light, extreme stress and the use of certain drugs.
Systemic lupus erythematosus, often abbreviated to SLE or lupus, that can affect any part of the body. Systemic lupus erythematosus (SLE) is an autoimmune disease, which means the body's immune system mistakenly attacks healthy tissue. This leads to long–term (chronic) inflammation. The underlying cause of autoimmune diseases is not fully known. SLE is much more common in women than men. It may occur at any age, but appears most often in people between the ages of 10 and 50. African Americans and Asians are affected more often than people from other races. SLE may also be caused by certain drugs.
SLE can be detected by Complete blood count, Erythrocyte sedimentation count, Antinuclear antibody test (detects the presence of autoantibodies).